Cytokine & Secreted protein spatial Isoform distribution in the Tumor MicroEnvironment
IR=Isoform Ratio (primary),
GC=Gene Counts (expression),
IC=Isoform Counts (combined)
| Gene | Tier | IR Sig | IR p-val | GC Sig | GC p-val | IC Sig | scRNA ΔPSI |
|---|
| Sample ID | Platform | Spots | Genes Tested | Genes Significant | Best Gene | Best p-value |
|---|
32,304 cells from glioma scRNA-seq dataset. PSI values quantified by MARVEL.
SE - Skipped Exon (exon included or excluded)MXE - Mutually Exclusive Exons (one or the other)A5SS - Alternative 5' Splice SiteA3SS - Alternative 3' Splice SiteAFE - Alternative First ExonALE - Alternative Last Exon| Gene | Event Type | Exon/Region | State 1 | State 2 | PSI 1 | PSI 2 | ΔPSI | padj |
|---|
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Export analysis results and source data.
Original data files in reports/ directory:
ont_splisosm_full_results.csv - ONT HSIC-IR resultspilot_splisosm_full_results.csv - SR HSIC-IR resultsscrna_full_psi_differential.csv - All PSI comparisonsspacet_isoform_correlations.csv - Cell type correlationsfinal_validation_report.csv - Validation tier summary